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Here’s a rundown of what was featured in the Deadpool Comic-Con trailer:

Wade Wilson (Reynolds) being told by his girlfriend Vanessa Carlysle (Morena Baccarin) that he can overcome his illness – to which Wade quipped, “You’re right. The cancer’s only in my liver, lungs, prostate, and brain. All things I can live without.”
To defeat his cancer, Wade enters the Weapon X program, asking them to do right by him – and, in an obvious cheeky reference to the Reynolds-starring Green Lantern, to not make his new superhero outfit “Green… Or animated.”
Footage from the live-action version of the ‘leaked’ Deadpool test footage sequence (see: Wade killing mercenary types on the highway).
Colossus knocking out Deadpool, who then calls his opponent a “big chrome c**k-gobbler.”
Deadpool killing several armed thugs atop a highway overpass, before he meets Negasonic Teenage Warhead (Brianna Hildebrand) for the first time. His response upon learning her name: “What the s**t?! That’s the coolest name ever!”
In a bit of fourth-wall knocking, Deadpool says “Cue the music,” as a montage of ‘our hero’ acting badly (dancing in a strip club, having wild sex with Vanessa) follows.
Weasel (T.J. Miller) comments on Wade’s new appearance, with lines like “You look like an avocado that had sex with an older avocado.”
Deadpool, upon slaughtering more people, sniffs his guns and turns to the camera to declare: “I’m touching myself tonight.”